Adansonia digitata L. is a multipurpose species in Africa and is used therapeutically, for food, economically and socioculturally. This study on the conservation status of Adansonia digitata L. is part of the development of strategies for the conservation and sustainable use of the species due to the importance of its socio-economic potential of the species. It aims to determine the different uses and their implication in the destruction of natural habitats of Baobab in Benin. The data were on the uses of fruits, peels and seeds carried out in the Guinean zone located between 6° 25"N and 7° 30" N and in the Sudanese zone located between 9° 45 "N and 12° 25" N. The results show that the fruits are rich in calcium (12.5-15%) and the populations consume the fruits directly or transformed into juice. The seeds are used in the preparation of broths and the bark is used in the production of strings. Crop losses ranged from 10-25%, 15-36% and 8-45% respectively for fruits, seeds and bark according to the climatic zones of the study. Ecologically, the species is found in dry forests, savannas and on agricultural land with a high capacity for resistance and adaptation to climatic variability. However, human threats reduce the range of the species and cause habitat loss. The uses of the different parts of the species must be regulated and rational.