The climate of the American Southwest is rapidly changing relative to other areas in the United States. Within the next 80 years, temperatures are expected to rise substantially and will be coupled with longer and more profound drought. How non-native plants may respond to these climatic changes is an important area of interest for land managers.This research examines an invasive plant and its microbe interactions under modeled climate projections. Particularly we are interested in the microbiome's impacts on non-native plant fitness and survival under climatic stress..  The African mustard (Strigosella africana ) is a recently spreading invasive that is of particular interest to regional land managers.. We first examined whether increased heat, drought conditions and/or fertilizer affected plant survivability. We found significant differences in plant survivability under differing heat and/or whether a drought was applied. Next, we collected full plant samples using sterile techniques and separated them by shoots and roots to have their DNA sequenced. Using this data, we were able to determine the natural microbiome of this plant. Our next steps will use the same climate models as before on plants grown from seeds collected in the field.  Plants from these trials will have their DNA sequenced and their microbial community structure will then be compared to the natural microbiome structure.