African Impatiens (Balsaminaceae) have long been recognized as a difficult taxonomic group because of high variation within some species and suspected hybridization. Considerable Impatiens diversity is found in Africa. Previously, three African clades have been identified, suggesting multiple colonizations of the continent. A small group represents descendants of the first dispersal events from Asia around 10 mya, but the majority of African Impatiens are descended from a third dispersal event around 5 mya. The mega-diverse Malagasy Impatiens are also included within this large clade. In the monograph of African Impatiens from 1980, 110 African taxa were recorded and dozens more have been described since then. We use target capture with Angiosperm 353 baits, extensively sampling the African taxa, to investigate the phylogenetic relationships within and among the African clades.